Page 1256 - Basic _ Clinical Pharmacology ( PDFDrive )

1242 Index

Stage fright, b-receptor antagonists for, 169 Structure-activity relationship, 35 Sulfonylurea receptor binding agents
Stalevo, 495, 500 Strychnine, 370t d-phenylalanine derivatives, 759, 768t
Staphylococcal beta lactamase-resistant Stuart-Prower defect, 622t meglitinide analogs, 759, 768t
penicillins, 800–801. See also Subarachnoid hemorrhage, 205 sulfonylureas, 757–759, 758t, 768t
Penicillin(s) Submucous plexus, 91f, 92 Sulfonylureas, 757–759, 768t
Staphylococcus aureus, transpeptidation Substance P efficacy and safety of, 758
reaction in, 798, 798f antagonists of, 317t, 318t first-generation, 758, 768t
State-dependent drug action, 236, 238f description of, 92t, 313–314 mechanism of action of, 757, 758t
Statins Substituted benzamides, 1106 second-generation, 758–759, 768t
description of, 632–634, 639t Substrate stabilization, 59 Sulfotransferases (SULTs), 63, 64f, 64t
OATP1B1 on metabolism of, 83 Succimer (dimercaptosuccinic acid, Sulfur, 1075
STATs (signal transducers and activators of DMSA), 1030f, 1030–1031 Sulfur dioxide, 1007, 1007t
transcription), 29, 29f arsenic poisoning treated with, 1027 Sulindac, 645t, 648–649
Status epilepticus, 432–433 lead poisoning treated with, 1024 Sulpiride, 515
Stavudine, 873t, 875 mercury poisoning treated with, 1029 Sulthiame, 432
Steam, 901 Succinylcholine, 488t Sumatriptan, 289–291, 290f, 291t, 296t
Stem cell transplantation, autologous, chemistry and structure of, 476, 476f Sunitinib, 966t, 969
603–604 clinical pharmacology of Sun protection factor (SPF), 1076
Stereoisomerism, 4 neuromuscular transmission assess- Sunscreens, 1076–1077
Sterilants, 898t, 901 ment in, 480–481 Superoxidized water, 900
Sterilization, 898t skeletal muscle paralysis in, 480 Supplements, dietary, 3, 1141–1144
Sterilox, 900 malignant hyperthermia from, 449, 483 coenzyme Q10, 1141–1142
Steroids, anabolic, 740–743, 745t. See also mechanism of action of, 478f–479f, definition of, 1132
Androgens and anabolic steroids 479t, 480 glucosamine, 1142–1143
Steroid synthesis inhibitors, 743, 745t pharmacokinetics of, 477–478, 478t historical and regulatory facts on, 1132
Sterol absorption inhibitors, 637, 640t properties of, 478t, 479t, 488t melatonin, 1143–1144
Stevens-Johnson syndrome (SJS), 83, 83t Sucralfate, 1095 regulation of, 1132
Stimulant laxatives, 1099 Sufentanil, 555t, 567, 572t. See also Opioid Suramin, 934
Stimulants, 144f, 150. See Amphetamines; agonists Surface area, in dosage calculations,
specific stimulant Sugammadex, 484 1056–1057, 1057t
Stiripentol, 431, 433t, 435 Sugars, nonabsorbable, 1098 Surgery, nausea and vomiting after,
Stones (calculi) Suicide inhibitors, 61 1104–1105, 1116t, 1117t
calcium oxalate, 789 Sulbactam, 806f, 806–807 Surgical anesthesia, 446
kidney Sulconazole, 1072 Susceptibility, organism, 906
from carbonic anhydrase inhibitors, Sulfacetamide, 836 Susceptibility testing, 906
261 Sulfadiazine, 835 Suspensions, 1054
from potassium-sparing diuretics, 267 Sulfadoxine, 835, 919f, 926 Suvorexant, 390b, 391, 394t
Stool surfactant agents (Softeners), 1098 Sulfadoxine-pyrimethamine, 920t Sweat glands, apocrine, 148
Strabismus, 118 Sulfamethoxazole, 835 Sympathetic nervous system, 90f, 90–91
Stratified medicine, 74 Sulfasalazine estrogens on, 725
Streptococcus pneumoniae, 592b description of, 652–653, 835 functions of, 137
Streptogramins, 822, 824t, 825t inflammatory bowel disease treated with, on renin release, 301
Streptokinase, 611, 611f, 618–619 1107, 1107f, 1116t Sympathetic sacral outflow, 93
Streptomycin Sulfate solution, 1098 Sympathomimetics, 137–155, 154t, 191t
description of, 827f, 829–830, 833t Sulfinpyrazone, 660f, 661 adrenoreceptors in, 138–142
tuberculosis treated with, 843t, Sulfonamides, 834–836, 840t alpha, 138f, 139, 139t
846–847, 851t adverse reactions of, 836 beta, 139t, 139–140, 140f
Stress-related gastritis, H 2 -receptor antago- chemistry of, 835f dopamine, 139t, 140
nists for, 1091 clinical uses of, 835–836 polymorphisms of, 142
Stress-related mucosal bleeding, 1094 mechanism of action and antimicrobial potencies of, 138
Strongyloidiasis activity of, 835f regulation of, 141
ivermectin for, 942 pharmacokinetics of, 835 selectivity and affinities of,
thiabendazole for, 946 preparations available, 840t 141, 141t
Strontium, for bone, 790t resistance to, 835 structure of, 138, 138f
Strontium ranelate, 780b trimethoprim and trimethoprim- asthma treated with, 349–352, 350f,
on bone homeostasis, 782 sulfamethoxazole mixtures of, 362t. See also specific drugs
osteoporosis treated with, 787 836–837, 840t beta 2 -selective, 351
Structural proteins, as drug receptors, 21 Sulfones, 850 preparations available, 363t