Page 1258 - Basic _ Clinical Pharmacology ( PDFDrive )

1244 Index

Tazarotene androgen suppression, 743, 744f, 745t mechanism of action of, 380
acne treated with, 1077 antiandrogens, 743–745, 745t rimonabant for dependence on, 588, 589t
psoriasis treated with, 1078 contraception in men, chemical Tetraiodothyronine (thyroxine, T 4 ), 687.
Tazobactam, 806f, 806–807 cyproterenone acetate, 745 See T4
Tbo-filgrastim, 606t fundamentals of, 745 Tetrathiomolybdate, 507
TCDD, 1013f, 1015 gossypol, 745 Tetrodotoxin, 370t, 464
Tedizolid, 823 preparations available, 745t Tezosentan, 220
Teduglutide, 1113 Testis, 740 Thalidomide, 15
Tegafur, 78, 79t Testosterone, 740–743 erythema nodosum leprosum treated
Tegaserod, 291 adverse effects of, 742–743 with, 850
chemical structure of, 1102f clinical uses of, 741t, 741–742 immunomodulatory derivatives of, 988
laxative action of, 1100 contraindications and cautions with, 743 immunosuppressive uses of, 987–988
Teicoplanin, 809, 812t mechanism of action of, 741 multiple myeloma treated with, 971
Telavancin, 803t, 809, 812t metabolism of, 740 phocomelia caused by, 1049
Telbivudine, 887 pharmacologic effects of, 741 T helper lymphocytes (TH1, TH 2 ), 980
Telcagepant, 315, 318t. See also Calcitonin physiologic effects of, 741 Theobromine
gene-related peptide preparations of, 741, 741t, 745t asthma treated with, 352–353
Telithromycin, 820–821, 824t synthesis of, 704f, 722f, 740 structure of, 352f
Telmisartan synthetic steroids with androgenic and Theophylline. See also Methylxanthine
hypertension treated with, 189 anabolic action, 741, 741t drugs
on vasoactive peptides, 316t in women, 732 asthma treated with, 352f, 352–353,
Temazepam, 385t, 393t. See also Testosterone cypionate, 740–743, 741t 362t
Benzodiazepines Testosterone enanthate, 740–743, 741t drug interactions of, 1172t
Temozolomide, 955t, 975 Tetanic stimulation, 479f, 481 in neonates, 1053t
Tendon xanthomas, 630 Tetanus immune globulin, 1181t poisoning with, 1041t, 1045
Tenecteplase, 619 Tetanus vaccines structure of, 352f
Tenofovir tetanus, diphtheria, pertussis (Tdap), Therapeutic index, 37
description of, 873t, 875–876 1178t Therapeutic window, 37
hepatitis B treated with, 887 tetanus-diphtheria (Td, DT), 1177t Thiabendazole, 939t, 946
Tenoxicam, 649 Tetrabenazine, 505, 508t Thiamine
Teratogens, 1051t. See also Pregnancy, Tetracaine, 460f, 461b, 472t acute ethanol withdrawal treated with,
pharmacology in Tetrachlorodibenzodioxin (TCDD), 1013f, 406t
definition of, 1050 1015 alcohol withdrawal syndrome treated
FDA risk categories for, 1052t Tetracyclic agents, 549t with, 403
Terazosin, 159, 159t, 170t, 184, 191t. chemistry of, 538–539, 539f Wernicke-Korsakoff syndrome prophy-
See also Adrenoceptor antagonist clinical pharmacology of laxis using, 403
drugs adverse effects in, 547 Thiazide diuretics, 177, 224t, 264f,
Terbinafine drug interactions in, 548t, 549 264–265, 273t. See also Diuretics
dermatologic pharmacodynamics of, 542t, 543 on bone homeostasis, 781
oral, 1074 pharmacokinetics of, 540t, 541 chronic heart failure treated with, 221
topical, 1072 preparations available, 551t heart failure treated with, 221
description of, 861, 861t Tetracyclines, 815–818, 824t idiopathic hypercalciuria treated with,
Terbutaline adverse reactions to, 818 788
asthma treated with, 351, 362t antimicrobial activity of, 816, 816f with loop diuretics, 269
structure of, 149f, 350f case study of, 815, 825 with potassium-sparing diuretics, 269
Terfenadine, 284 clinical uses of, 817–818 preparations available, 274t
Teriflunomide, 988–989 dosing of, 818 Thiazolidinediones, 760–761, 768t
Teriparatide, 775, 780b, 787, 790t mechanism of action of, 816, 816f Thick ascending limb, 257, 257f
Terlipressin, 308. See also Vasopressin pharmacokinetics of, 817 Thienopyridines, 620
receptor agonists preparations available, 825t Thiethylperazine, 1105–1106
variceal hemorrhage treated with, 1114 resistance to, 816–817 Thimerosal, 901
on vasoactive peptides, 317t structure and chemistry of, 815–816 Thioamides, 693–695, 694f, 701t
Tertiary amine, 9, 60t Tetraethylammonium (TEA), 133–134, Thiocyanate, 199
Testicular cancer, 974 134f. See also Ganglion blockers 6-Thioguanine (6-TG), 81, 958t, 960–961
9
Testicular hormones, 740–745, 745t. Δ -Tetrahydrocannabinol (THC) Thiols, 340–341
See also specific hormones for analgesia, on ion channels, 560b Thiopental, 450f, 450t
androgens and anabolic steroids, G io protein-coupled receptor activation Thiophosphate insecticides, 117
740–743, 741t, 745t by, 577t, 582, 583f 6-Thiopurines, 958t, 960–961, 961f