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CHAPTER 34 Drugs Used in Disorders of Coagulation 625
C ASE STUD Y ANSWER
This patient has pulmonary embolism secondary to a without monitoring. As this situation can be considered a
deep venous thrombosis (DVT). Options for treating this provoked event given the history of oral contraceptive use,
patient include unfractionated heparin or low-molecular- the recommended duration of therapy would be 3–6 months
weight heparin followed by warfarin, with INR goal of depending on individual risk factors and preferences. The
2–3; parenteral anticoagulation for 5–7 days followed by patient should be counseled to use an alternative form of
edoxaban; or rivaroxaban, apixaban, or dabigatran alone contraception.