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CHAPTER 34  Drugs Used in Disorders of Coagulation        625


                       C ASE  STUD Y  ANSWER


                       This patient has pulmonary embolism secondary to a   without monitoring. As this situation can be considered a
                       deep venous thrombosis (DVT). Options for treating this   provoked event given the history of oral contraceptive use,
                       patient include unfractionated heparin or low-molecular-  the recommended duration of therapy would be 3–6 months
                       weight heparin followed by warfarin, with INR goal of   depending on individual risk factors and preferences. The
                       2–3; parenteral anticoagulation for 5–7 days followed by   patient should be counseled to use an alternative form of
                       edoxaban; or rivaroxaban, apixaban, or dabigatran alone   contraception.
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