Page 960 - Basic _ Clinical Pharmacology ( PDFDrive )

946 SECTION VIII Chemotherapeutic Drugs

Adverse Reactions, Contraindications, PREP AR A TIONS
& Cautions A V AIL ABLE
Pyrantel’s adverse effects are infrequent, mild, and transient.
They may include nausea, vomiting, diarrhea, abdominal cramps, GENERIC NAME AVAILABLE AS
dizziness, drowsiness, headache, insomnia, rash, fever, and weak- Albendazole Albenza
ness. Pyrantel should be used with caution in patients with liver Bithionol Bitin
dysfunction, as transient aminotransferase elevations have been Diethylcarbamazine Hetrazan
noted. Experience with the drug in pregnant women and children Ivermectin Mectizan, Stromectol
younger than 2 years is limited. Mebendazole Generic, Vermox
Metrifonate Trichlorfon, Bilarcil
Niclosamide Niclocide
THIABENDAZOLE Oxamniquine Vansil, Mansil
Oxantel pamoate Quantrel
Thiabendazole is an alternative to ivermectin or albendazole for Oxantel/pyrantel pamoate Telopar
the treatment of strongyloidiasis and cutaneous larva migrans. Piperazine Generic, Vermizine
Praziquantel Biltricide; others outside the USA
Basic Pharmacology Pyrantel pamoate Ascarel, Pamix, Pin Rid, Pin-X
Thiabendazole Mintezol
Thiabendazole is a benzimidazole compound. Although it is a
chelating agent that forms stable complexes with a number of
metals, including iron, it does not bind calcium. Thiabendazole
is rapidly absorbed after ingestion. With a standard dose, drug REFERENCES
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