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CHAPTER 53 Clinical Pharmacology of the Antihelminthic Drugs 947
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Supplement. mebendazole, albendazole plus oxantel pamoate, and mebendazole alone
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C ASE STUD Y ANSWER
The presentation is highly suggestive of cystic hydatid and positive serology support the diagnosis, and treatment
disease (infection with Echinococcus granulosus), which is generally entails albendazole in conjunction with cautious
transmitted by eggs from the feces of dogs in contact with surgery or percutaneous aspiration. One approach entails
livestock. Other causes of liver fluid collections include ame- treatment with albendazole followed by aspiration to con-
bic and pyogenic abscesses, but these are usually not cystic firm the diagnosis and, if it is confirmed, to remove most of
in appearance. For echinococcosis, a typical cystic lesion the infecting worms.