Page 189 - Atlas of Histology with Functional Correlations
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Are antigen-presenting cells to lymphocytes for immunologic response

                   Derived from circulating blood monocytes
                   Called Kupffer cells in liver, osteoclasts in bone, microglia in central nervous
                   system, Langerhans cells in skin, monocytes in blood, and osteoclasts in bone



               Lymphocytes



                   Most numerous in loose connective tissue of respiratory and gastrointestinal
                   tracts
                   Produce antibodies to kill infecting cells



               Plasma Cells



                   Characterized by chromatin distributed in radial pattern
                   Derived from B lymphocytes exposed to antigens
                   Produce antibodies to destroy specific antigens



               Mast Cells



                   Closely associated with blood vessels

                   Found in skin, respiratory, and digestive system connective tissue
                   Ovoid cells with fine, regular basophilic granules
                   Release  histamine  and  vasoactive  chemicals  when  exposed  to  allergens,
                   causing immediate hypersensitivity allergic response

                   Contain also weak anticoagulant heparin


               Neutrophils



                   Active phagocytes; engulf and destroy bacteria



               Eosinophils



                   Increase after parasitic infestation
                   Phagocytize antigen–antibody complexes during allergic reactions



               COLLAGEN FIBERS





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