Page 223 - Atlas of Histology with Functional Correlations

are the large adipose cells (5) with large vacuoles (because of fat removal during

section preparation) and a small, peripheral cytoplasm that surrounds the
nucleus (5). Other identifiable cells in the bone marrow are the very large
megakaryocytes (9, 10) with varied nuclear lobulation. One of these
megakaryocytes (10) is situated adjacent to a blood sinusoid, into which the
fragments from its cytoplasmic extensions separate and discharged as platelets.

Selected blood cells from the red bone marrow are illustrated on the next
page at a higher magnification.

FIGURE 6.12 ■ Development of different blood cells in the red bone marrow

(decalcified). Stain: hematoxylin and eosin. Upper image: high magnification;
lower image: oil immersion.

Figure 6.13 | Bone Marrow Smear: Development

of Different Cell Types

A bone marrow smear shows a few typical blood cells in different stages of
development. In the erythrocytic series, the precursor cell proerythroblast (3)

exhibits a thin rim of basophilic cytoplasm and a large, oval nucleus that

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