Page 781 - Atlas of Histology with Functional Correlations
P. 781

Juxtaglomerular apparatus in kidney initiates the renin–angiotensin pathway

                   to increase blood pressure
                   Aldosterone increases sodium reabsorption and increased water retention by
                   distal convoluted tubules
                   Increased fluid volume increases blood pressure and inhibits further release
                   of aldosterone

                   Cells  of  zona  fasciculata  secrete  glucocorticoids,  of  which  cortisol  and
                   cortisone are important
                   Glucocorticoids are released in response to stress, increase metabolism and

                   glucose levels, and suppress inflammatory responses
                   Cells of zona reticularis produce weak androgens that influence development
                   of secondary sex characteristics



               Medulla



                   Cells are modified postganglionic sympathetic neurons that became secretory
                   Stain with chromium salts and are called chromaffin cells
                   Medulla  cells  can  be  considered  as  ganglion  cells  without  dendrites  and
                   axons

                   Action controlled by sympathetic division of autonomic nervous system, not
                   pituitary gland
                   Cells contain catecholamines (epinephrine and norepinephrine) and respond

                   to stress
                   Prepares the individual for flight-or-fight response
                   Cells activate maximal use of energy and physical effort

































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