Page 93 - Pharmaceutical Organic Chemmistry-3 (Theoritical book) 24-25

Clinical Pharmacy PharmD - 2024/2025 Level 2 Pharmaceutical Organic Chemistry-3 (PC 305)

❖ NMR Multiplicity (Splitting): It is the number of lines forming a single NMR peak.

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❖ Each type of H senses the number of H on the neighboring carbon(s).
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❖ The signal of one H splits into n + 1 peaks, where n = number of H on neighboring
carbons(s).
❖ Equivalent protons act as a group; they will give one NMR peak with splitting related

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to No. of H on neighboring carbons(s).
❖ Splitting patterns are singlet (s), doublet (d), triplet (t), quartet (q), pentet (p),

sextet,……..

❖ Splitting could be called multiplet (m) in case of splitting higher that quartet (q).