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                      Triple combination therapy reduces blood pressure

                         significantly in diverse hypertension subgroups












                              n      1.134         275          414          378          113
              Mean baseline BP     165.8/97.7   168.6/95.4   168.0/98.3   164.5/96.1   160.0/80.3

                              0      Overall      Elderly      Obese       Diabetes       ISH

                             -5
                                                                                            -5.9
                             -10
                           Mean reductio in msSBP and msDBP, mmHg  -15  -17.8  -16.5  -18.4  -16.6




                             -20


                             -25


                             -30

                             -35
                                                                         -34.4        -30.2
                                  -36.6
                             -40               -38.5        -38.5                          Systolic BP


                             -45                                                           Diastolic BP


                        Mean reductions in msSBP and msDBP at 26±8 weeks in subgroups treated with Aml/Val/HCT.










                        9,794 patients analyzed, 8,603 and 1,191 patients were prescribed Aml/Val and Aml/Val/HCT, respectively.





              CI: confidence interval, LL: lower limit, UL: upper limit.
              Vasc Health Risk Manag. 2010;6: 821–827
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