Page 127 - Physiology and Pathophysiology MNU 2024-2025 نظرى
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Clinical pharmacy 2024/2025                  Level 2 Pharm D                       Physiology and Pathophysiology
           (MD303)


                                             II- Urinary Incontinence

           In  this  condition there  is  involuntary  passage  of  urine  due  to  defective  voluntary  control  of  the
           external urethral sphincter.

                1. Stress incontinence         2.Retention and overflow            3. Urge incontinence
                                                     incontinence
            ✓ This is leakage of urine      This occurs when there is:       ✓  Is a sudden and strong
               when intra-abdominal         ▪ Retention of urine due to         need to urinate.
               pressure is raised, e.g. on    obstruction of urinary         ✓  It may also refer to as an
               coughing, laughing or          outflow, e.g. enlarged            unstable or overactive
               sneezing.                      prostate.                         bladder.
            ✓ It usually affects women      ▪ Neurological abnormality       ✓  Leakage of urine follows a
               when there is weakness of      affecting the nerves involved     sudden and intense urge to
               the muscles of the pelvic      in micturition, e.g. stroke,      void and may be due to a
               floor e.g. after childbirth or   spinal cord injury or multiple   urinary tract infection,
               as part of the ageing          sclerosis.                        calculus, tumor, or
               process.                                                         neurologic disorder.
















































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