Page 210 - Physiology and Pathophysiology MNU 2024-2025 نظرى

Clinical pharmacy 2024/2025 Level 2 Pharm D Physiology and Pathophysiology (MD303)

Brush border enzymes
• Act on the brush border.
• As Amino peptidase, Carboxy peptidase, tripeptidase &
dipeptidase

Digests oligopeptides into amino acids

Absorption

Amino acids are absorbed by active transport  portal vein  liver.

3- Lipid digestion:

In mouth No digestion

In stomach Little or no digestion

The main site of digestion

➢ Gall bladder secretes Bile salts  emulsify fat.
In intestine
➢ Digestion by pancreatic lipase  digests fats into glycerol, fatty

acids & monoglycerides.

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