Page 79 - Physiology and Pathophysiology MNU 2024-2025 نظرى

Clinical pharmacy 2024/2025 Level 2 Pharm D Physiology and Pathophysiology (MD303)
I. Pancreatic Hormones

The pancreas is an exocrine gland & an endocrine gland.

The exocrine tissue The endocrine tissue

islets of Langerhans
produces a bicarbonate ♠ make up only 2 to 3% of the mass of the pancreas.
solution & digestive
enzyme  transported to ♠ blood carrying the pancreatic hormones  transported
through the hepatic portal vein  delivered directly to the
the small intestine 
digestion of food. liver where the hormones carry out many of their metabolic
effects.

Pancreatic islets (Langerhans islet)

B-cell α-cell delta-cell

Secretes insulin Secretes glucagon Secretes somatostatin.

only hormone  blood antagonizes the effects of Inhibits release of both
glucose level insulin. insulin & glucagon.

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