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Clinical pharmacy 2024/2025                   Level 2 Pharm D                       Physiology and Pathophysiology (MD303)

                                                                       Renal Physiology



                                 Kidney Function                                                          Structure of the Kidney
        1.  Primary function.                                                                        ▪  Contains many capillaries.
                                                                                   Outer cortex
            Regulate ECF (plasma and interstitial fluid) through formation of
                                                                                                     ▪  Renal pyramids separated by renal columns.
            urine.
        2.  Regulate volume of blood plasma & BP.                                                    ▪  Pyramid  contains  minor  calyces  which  unite  to  form  a
        3.  Regulate [waste products] in the blood.                                                      major calyx.
                                                                       +
                                                                    +
        4.  Regulate PH (Regulate concentration of electrolytes. Na , K , and        Medulla
                                                                                                     ▪  Major calyces form the renal pelvis.
                 -
            HC03 and other ions).
        5.  Secrete hormones (erythropoietin-renin).                                                 ▪  The Renal pelvis collects urine.
                                                                                                     ▪  Transports urine to ureters.




























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