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Clinical pharmacy 2024/2025             Level 2 Pharm D                       Physiology and Pathophysiology (MD303)

 Renal Physiology



 Kidney Function      Structure of the Kidney
 1.  Primary function.   ▪  Contains many capillaries.
 Outer cortex
 Regulate ECF (plasma and interstitial fluid) through formation of
                 ▪  Renal pyramids separated by renal columns.
 urine.
 2.  Regulate volume of blood plasma & BP.   ▪  Pyramid  contains  minor  calyces  which  unite  to  form  a
 3.  Regulate [waste products] in the blood.    major calyx.
 +
 +
 4.  Regulate PH (Regulate concentration of electrolytes. Na , K , and   Medulla
                 ▪  Major calyces form the renal pelvis.
 -
 HC03 and other ions).
 5.  Secrete hormones (erythropoietin-renin).   ▪  The Renal pelvis collects urine.
                 ▪  Transports urine to ureters.




























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