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Clinical pharmacy 2024/2025                            Level 3 Pharm D                             Pharmacology 1 (PO 502)

                                      6- Yohimbine (selective α2 blocker)

               Promoting NE release & improve symptoms in painful diabetic neuropathy.

                                 7- Ergot alkaloids (has α blocking activity)


            1-  Ergotamine & dihydroergotamine                              ttt of migraine.

            2-  Dihydroergotoxine (Hydergine) &                Improve senile cerebral insufficiency.
               Ergotoxine

                                                            Uterine contraction ➔ prevention & ttt of
            3-  Ergonovine & methylergonovine/                postpartum hemorrhage (action is more
               methylergometrine (Methergine)
                                                                     prolonged than oxytocin).

                                                              Dopamine agonist ➔ in parkinsonism &
            4-  Bromocriptine (Parlodel):
                                                                         hyperprolactinemia.







































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