Page 132 - Phytochemistry 2 (06-PG 605)

B- Other carcinogens

 Genetic factors, inherited mutation, oncogenes

(cancercausing genes) and defective tumour
suppressor genes.

 Life style factor e.g. high fat, low fiber diet,

ethanoldrinking and tobacco smoking

 Food

 Food additives, preservatives ( nitrates & nitrites).

NNC are formed by nitrosation (in stomach) of amines
oramides(degradation products of protein, foods,
medicins)with nitrates (formed by saliva bacterial
reduction of nitrites present in food or preservatives or
water ).