Page 84 - Phytochemistry 2 (06-PG 605)

Ergot alkaloids of pharmaceutical importance
The most widely medicinally used ergot alkaloids are
ergometrine and ergotamine.

Ergometrine (Ergonovine, Ergobasine)

HN OH
O
NMe
H

N
H

Ergometrine

Uses
Ergometrine causes vigorous contraction of the uterus. It is

mainly used as an oxytocic in order to aid delivery or to prevent
postpartum hemorrhage.

Lysergic acid diethylamide (LSD)

Another example of this class of simple amides is the famous
hallucinogen (LSD) which is lysergic acid diethylamide. It is a semi
synthetic drug with a very potent action on the CNS in extremely
small doses.

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