Page 36 - phytochemistry II -pharmD general

Pomegranate alkaloids
Pelletierine
Source:The bark and fruit rind of Pomegranate tree,
Pelletierine is an oily colourless volatile liquid

Pelletierine
Uses
Pelletierine tannate is official in the E.P.
It is mainly used as anthelmintic drug against pork tape worms and Ascaris
The tannate form of pelletierine is used because it is less soluble in GIT, so it is
less able to be absorbed (local action).
Conium alkaloids

coniine
Source: isolated from hemlock fruits ( Conium maculatum).
The juice from hemlock plant was a primary constituent used by ancient Greeks
in executing criminals.
An extract of hemlock was used to cause the death of Socrates around 400 BC
The major alkaloid of hemlock is coniine. It is a toxic, liquid volatile alkaloid with
characteristic mice-like odor
Uses

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