Page 41 - phytochemistry II -pharmD general
P. 41

• Cephaeline and psychotrine are phenolic alkaloids.
   • Ipecoside is a gluco-alkaloids with one molecule of sugar

Properties of ipecacuanha alkaloids
Emetine

   ❑ Non-phenolic
   ➢ Insoluble in aqueous solution of fixed alkali.
   ❖ soluble in ether
Cephaeline
   ❑ Phenolic
   ➢ Soluble in aqueous solution of fixed alkali.
   ❖ Soluble in ether
   • It gives emetine upon methylation.
Psychotrine
   ❑ Phenolic
   ➢ Soluble in aqueous solution of fixed alkali.
   ❖ Insoluble in ether
   • On reduction it is converted to cephaeline

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