Page 112 - COMMUNITY PHARMACY PRACTICE

02/04/2024

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Castor oil……

Cathartic effects (excessive fluid and electrolyte loss) leading to
dehydration. It is mainly used to evacuate the GIT contents prior to GIT
operations.
Warning
It shouldn't be used in pregnants as it may cause premature labor.
• It can erode intestinal villi or disorganize the microvillous surface of the

intestinal lumen so long term use leads to nutrient malabsorption.
• Dose :- adult: - 15-60 ml children (2-12 years) 5-15ml
N.B
• Castor oil can be misused to hasten delivery to induce premature

uterine contractions;
• however this is deadly since it can cause amniotic fluid embolism and

impaired health of the infant

•.

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Lubricant laxatives:

Mechanism of onset of action: Examples &
action marketed
• 6-8 hr orally. products
• at the colon to • 5-15 minutes
increase water • (mineral oils) as
retention in the rectally. liquid paraffin
stool (coat)to
soften it

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