Page 110 - COMMUNITY PHARMACY PRACTICE
P. 110

02/04/2024

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        Side            • Gas bloating
     effects of         • Flatulence.
     lactulose
                        • Excessive dosage
                          lead to

                        • Diarrhea,
                          Hypokalemia

                        • Infants receiving
                          Lactulose may
                          develop
                          Hyponatremia and
                          dehydration

224

                                                             225

                        Stimulant laxatives

        Mechanism of      onset of action:     Examples &
              action                            marketed
                        • oral preparations      products
     • work in the        ( 6 to 12 hr)
       small and                               • Anthraquinone
       large            • rectal ones ( 15 to  laxatives as senna
       intestines to      60 mins).            (Sennalax ®tablet),
       stimulate
       bowel motility   • They are effective   • Bisacodyl (Bisadyl®
                          as initial therapy   tablets               and
     • increase the       to treat             suppositories)diphen
       secretion of       constipation.        y-lmethane
       fluids into the                         derivative.
       bowel.
                                               • enteric coated ?).

                                               • Castor oil

                                               • Sodium Pico sulfate
                                                 (Picolax®oral drops)
                                                 ..safest

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