Page 215 - COMMUNITY PHARMACY PRACTICE
P. 215
02/04/2024
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Contraindications (ASA)
• Patients with risk factors for upper GI bleeding should
avoid selftreatment with ASPIRIN. These risk factors
include
(1) History of uncomplicated or bleeding peptic ulcer;
(2) age older than 60 years;
(3) concomitant use of aspirin or other NSAIDs,
anticoagulants, antiplatelet agents, bisphosphonates,
selective serotonin reuptake inhibitors, or systemic
corticosteroids;
(4) infection with helicobacter pylori;
(5) rheumatoid arthritis;
(6) NSAIDrelated dyspepsia; and
(7) concomitant use of alcohol.
• All salicylates should be avoided in patients with a
434 history of gout or hyperuricemia because of doserelated
effects on renal uric acid handling.
435
Other Side effects (ASA):
¨GI upset and renal dysfunction.
¨Ringing of ear (Tinnitus).
¨Hypersensitivity reactions in some patients with
salicylate allergy.
¨Aspirin induced asthma.
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