Page 212 - COMMUNITY PHARMACY PRACTICE
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02/04/2024
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Maximum daily dose(FDA)
• 3251000 mg every 46 hours (suggested 3250
mg)
• However, a maximum daily dosage of 3000-3250 mg is
allowed for acetaminophen labeling.
• combination drug products contain ……………..
milligrams (mg) of acetaminophen per tablet, capsule,
or other dosage unit.(FDA)
• Max 2g daily for liver diseases!
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ACETAMINOPHEN (PARACETAMOL)
Adverse reactions:
¨ In recommended doses, paracetamol is considerd safe. It does not
irritate the lining of the stomach, affect blood coagulation much as
NSAIDs, or affect function of kidneys.
¨ In some cases of over dose it causes hepatotoxicity.
¨ Methionine and N-acetylcysteine are effective antidotes for
paracetamol poisoning.
¨ Paralex Plus® &Hepamol F.C® contain both paracetamol and
methionine. For pts with hepatic problems
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