Page 32 - Pharmaceutics III_ 02-06-01304_Fall 2025_ Pharm D_Electronic book
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3. Compression coating
    4. Enteric coating
    5. Sustained release coating

1. Sugar Coating:
It consists of several sequential steps applied in traditional coating pans.
Steps:

    1. Sealing: protect tablet core from moisture by applying shellac or polymer in organic
         solvent.

    2. Sub-coating: builds up size using gelatin or acacia with sugar and calcium carbonate.
    3. Smoothing: smooth surface by applying syrup solution.
    4. Coloring: color syrup added to obtain desired shade.
    5. Polishing: with waxes such as beeswax, carnauba wax for gloss.

Disadvantages of sugar coating:
    • Tedious and time-consuming (may take hours).
    • Needs skilled operator.
    • Increases tablet weight by up to 50%.

2. Film coating:
A single, thin, continuous film (10–20 µm) is formed around each tablet using polymeric
solution or dispersion.
Advantages:

    • Shorter process time.
    • Weight increase only 2–3%.
    • More reproducible and automated.
Film coating composition:
    • Film-forming polymer: HPMC, HPC, EC, CAP, PVAP, acrylic polymers (Eudragit).
    • Plasticizer: PEG 400, glycerin, propylene glycol, castor oil.
    • Colorant: Titanium dioxide, lake pigments.
    • Solvent: Water, ethanol, isopropanol or mixtures.

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