Page 219 - Pharmaceutics IV (02-06-01305)
P. 219
30/03/2024
Many a Number of drugs (non peptides), like cyanocobalamin, a
drugs can hematopoietic; and nicotine as an adjunct in smoking cessation.
be rapidly
absorbed Or more poorly absorbed orally (scopolamine, hydralazine,
through progesterone, and propranolol ) or
the nasal
mucosa Drugs with extensive pre-systemic metabolism, such as
with a progesterone, estradiol, propranolol, nitroglycerin, sodium
systemic chromoglyate
bioavailabi
lity of Great promise for the administration of insulin, vaccines, and a
approxima number of other polypeptides and proteins. (Why)that are
tely 100%: subject to destruction by the gastrointestinal fluids and are
administered onlyDrbALyyaainRajmeacdtanio, AnU 13
13
The major advantages of nasal administration
include the fast absorption, rapid onset of
action, and avoidance of hepatic and intestinal
first-pass effects.
Dr ALyaa Ramadan, AU 14
14
7
