Page 256 - Pharmaceutics IV (02-06-01305)
P. 256
3/30/24
TypesTypoesfof pProperlloansp? ellant?
HC Flammable,
(Hydrocarbon) immiscible
with H2O
Liquefied CFHC Non-
gases (Freon) flammable,
deplete ozone
Propellant HFA Ozone
(Hydrofluoroalkane) friendly, low
v.p
Compressed N2O ,CO2 More
gases ,N2 new
liquified
Does it differ in the design of aerosol gases?
container when the propellant is CFCs or bonus
HCs?
Prof Alyaa Ramadan, ceutics, AU
19
Hazards of Freon , CFHC
To the Patient Environment
Ozone depletion So
• Irritation of pharynx
and bronchi if inhaled increase amount of
ultraviolet radiation
(other propellant as reaching the earth so
well but lesser extent) increase incidence of skin
• Sometimes cardiotoxic
cancer
(repeated use)!
Prof Alyaa Ramadan, ceutics, AU
20
10