Page 255 - Pharmaceutics IV (02-06-01305)
P. 255

3/30/24

    Two phase system

    The picture can't be displayed.

                                                                                                        Liquid phase    Vapour phase
                                                                                                       (propellant and

                                                                                                           drug) *

                                                                                                        (dispersion or emulsion)
                                                                                                       *With or without cosolvent

                                                                      Prof Alyaa Ramadan, ceutics, AU

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    Three phase system

    Vapour                           Vapour
    phase                            phase

    Liquid phase (liquefied          Liquid phase (liquefied
         gas propellant)                   gas product)

     Liquid phase (aqueous           Solid phase(drug particle
      drug solution of drug               suspended in the
    which is immiscible with                 propellant)

          the propellant)

     Because the liquefied propellant usually has a greater density than the
    aqueous layer, it generally resides at the bottom of the container with the

           aqueous phase floatingPraofbAolyvaaeRa(mnadeaen,dcefutoicrs, dAUip tube?? Or not??)

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