Page 255 - Pharmaceutics IV (02-06-01305)
P. 255
3/30/24
Two phase system
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Liquid phase Vapour phase
(propellant and
drug) *
(dispersion or emulsion)
*With or without cosolvent
Prof Alyaa Ramadan, ceutics, AU
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Three phase system
Vapour Vapour
phase phase
Liquid phase (liquefied Liquid phase (liquefied
gas propellant) gas product)
Liquid phase (aqueous Solid phase(drug particle
drug solution of drug suspended in the
which is immiscible with propellant)
the propellant)
Because the liquefied propellant usually has a greater density than the
aqueous layer, it generally resides at the bottom of the container with the
aqueous phase floatingPraofbAolyvaaeRa(mnadeaen,dcefutoicrs, dAUip tube?? Or not??)
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9