Page 257 - Pharmaceutics IV (02-06-01305)
P. 257

3/30/24

        AEROSOL SYSTEMS

    The pressure of an aerosol is critical to its
    performance:
    It can be controlled by
    (a) the type and amount of propellant (next slide)
    (b) the nature and amount of product concentrate

                                                                      Prof Alyaa Ramadan, ceutics, AU

21

   Aerosol performance variables

    • Space sprays generally contain a greater proportion of
       propellant than do aerosols intended for surface coating
       and foam aerosols contain lesser amount.

    • Blends of the various liquefied gas propellants are
       generally used in pharmaceutical aerosols to achieve
       the desired vapor pressure and to provide the proper
       solvent features for a given product.

                                                                      Prof Alyaa Ramadan, ceutics, AU

22

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