Page 257 - Pharmaceutics IV (02-06-01305)
P. 257
3/30/24
AEROSOL SYSTEMS
The pressure of an aerosol is critical to its
performance:
It can be controlled by
(a) the type and amount of propellant (next slide)
(b) the nature and amount of product concentrate
Prof Alyaa Ramadan, ceutics, AU
21
Aerosol performance variables
• Space sprays generally contain a greater proportion of
propellant than do aerosols intended for surface coating
and foam aerosols contain lesser amount.
• Blends of the various liquefied gas propellants are
generally used in pharmaceutical aerosols to achieve
the desired vapor pressure and to provide the proper
solvent features for a given product.
Prof Alyaa Ramadan, ceutics, AU
22
11