Page 278 - Pharmaceutics IV (02-06-01305)
P. 278

3/30/24

        So Factors influencing the
    effectiveness of aerosol therapy

       Device design (e.g.     Properties of the sprayed
    Liquid and gas flow rate)       system (liquid or

                                  suspension), such as
                               concentration, viscosity,
                               density or surface tension

    Size distribution of the   Dynamics of inhalation,
      aerosol particles and     i.E. The frequency of
    their physical properties
    (hygroscopicity, density,  breathing or the volume
    shape and morphology)            of air inhaled.

    Prof Alyaa Ramadan, ceutics, AU

63

  Factors affecting bioavailabilty

Bioavailability??
The rate and extent
to which the active
ingredient or active
moiety is absorbed
from a drug product
and becomes
available at the site
of action. ??

                                                                      Prof Alyaa Ramadan, ceutics, AU

64

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