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Limitations of Friedel-Crafts alkylation
2. Poly-alkylation
It occurs frequently with F.C. alkylation because the introduced alkyl group
activates the ring towards further substitution.
Alkyl benzene is more reactive than benzene.
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Limitations of Friedel-Crafts alkylation
3. F.C alkylation and acylation reactions usually give poor yields when powerful
EW groups are attached to the aromatic ring
Deactivating groups
They give poor yields in Friedel Crafts reactions because
the ring is electron deficient
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