Page 280 - Biochemistry PharmD General

Disorders related to abnormalities in the synthesis
of porphyrins

Porphyria’s

Porphyria’s are a group of diseases in which there is
an increased excretion of porphyrins or porphyrin
precursors (intermediates of porphyrin synthesis).
About 85% of heme synthesis occurs in erythrocyte
precursors and 15% in liver. Therefore porphyria’s are
classified into two types (1) Erythropoietic and (2)
Hepatic. Some of them are inherited while others are
acquired.

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