Page 281 - Biochemistry PharmD General
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Hemoglobin Derivatives
There are some derivatives of normal Hb that arise due
to metabolic changes in the RBC.
The various hemoglobin derivatives are
1. Oxyhemoglobin (HbO2)
The main function of hemoglobin is to transport oxygen
from the lung to the tissues. In lungs the partial
pressure of oxygen is 100 mm of Hg, at this pressure
hemoglobin is 95-96% saturated with oxygen. On
binding with O2 in the lungs hemoglobin is converted to
oxy-hemoglobin (Hb02). O2 is bound to heme iron.
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