Page 66 - Practical Handout bio 2 mnu 2025_Neat
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Level two – Semester 4 - PharmD Biochemistry-II PB-403 (Practical course) 2024/2025
Serum and urine glucose level
In normal conditions:
✓ Fasting blood glucose level is 70-110 mg/dl.
✓ Postprandial blood glucose level is < 140 mg/dl.
✓ Absent in the urine, as the renal threshold level is > 180 mg/dl in
normal condition.
Sources of blood glucose: Fates of blood glucose:
1. Dietary carbohydrate. 1. Oxidation
2. Glycogenolysis 2. Glycogenesis
3. Gluconeogenesis 3. Lipogenesis
Examples of physiological changes in serum glucose concentration
Increased fasting glucose Decreased fasting glucose
concentration in: concentration in:
Normal pregnancy:
(mild hypoglycemia).
Severe hypoglycemia occurs in
Due to the increased adrenaline
normal neonates born to diabetic
level in the circulation:
mothers.
❖ Hard physical activity.
Within 2-4 hours postnatally, blood
❖ Strong emotions, e.g., fear.
glucose falls to the lowest level,
returning to the birth value in 3-5
days.
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