Page 13 - Pharmaquest issue 1 2020
P. 13

ANTIBIOTICS RESISTANCE;
      A GLOBAL ISSUE

      AJAYA ACHARYA,

      BATCH 2016



      Broadly speaking, antibiotics are a

      group of chemicals or  substances
      produced by various species of
      microorganisms (bacteria, fungi, and
      actinomycetes) that suppress the growth

      of other microorganisms or destroy
      the microorganism ,used mostly at low
      concentration   in treatment of various
      bacterial infections diseases. Classes of

      antibiotics are available ranging from
      narrow spectrum to broad spectrum
      antibiotics that covers a few amount of
      pathogens; bacteria to wide variety of

      bacteria, for suppressing bacterial growth
      (bacteriostatic) or for killing bacteria
      (bactericidal). Generally, because of wide
      coverage and prevention on infections

      caused by  gram –ve  & gram +ve bacteria,
      a broad spectrum antibiotics, that are
      both bacteriostatic and bactericidal like
      penicillin, cephalosporin, tetracycline,                 This type of resistance offered by bacteria

      ciprofloxacin, and levofloxacin etc. are                 towards antibiotics for treatment of any
      frequently used from years ago to till now. ailments nowadays called antibiotics
      But because of frequently misuse or                      resistance by bacteria. As we know,
      overuse of antibiotics for treatment of                  “Darwin’s theory of evolution or

      minor ailments from years to till now,                   Darwinism -Competition and struggle for
      nowadays bacteria are struggling and                     existence (Darwinism or Theory of natural
      modifying on their cellular structures or                selection, pp. 35-40)”- somehow related
      cells bio-chemistry for to defend, adapt &  as ,for bacteria to survive and exist on

      become more resistant to such antibiotics  nature from adverse effects of antibiotics
      for their survive-ness and existence, as a               , they need to modify their biochemical
      result bacteria becoming more resistible                 structures for Better adaptation and hence
      to same type of frequently used earlier                  they have been resistant

      antibiotics and it’s difficult to treat minor            to different types of antibiotics nowadays
      diseases nowadays that was cured earlier by in world, which are the major problems
      same antibiotics at same dose strength.                  for any health and medicine professionals
                                                               to cure from normal diseases using same

                                                               strength of same type of antibiotics.
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