Page 14 - Pharmaquest issue 1 2020

For eg. Carbapenem-resistant situations to tackle to such resistant
Enterobacteriaceae (CRE) are the bacteria. As a result unknowingly
group of bacteria that are more increase in use of antibiotics day
virtually resistant to almost all by day is not only making the risk
antibiotics including carbapenems, in health conditions of patients
because of developing an enzyme but also has become challenging
called New Delhi metallo-beta- issues to us, leading slowly towards
lactamase (NDM-1) , thus nowdays a global crisis. Rapidly emerging
a diseases caused due to CRE are resistant bacteria has threatened the
almost untreatable or very difficult to extraordinary health benefits that
treat and increased in death patients have been achieved with antibiotics
number due to CRE infection have use. If this rate of using antibiotics
rising due to antibiotic resistant. persists, then there may be possible
According to a journal published of arriving again an era where
on PubMed central (PMC), USA bacteria rules the world against us,
titled The Antibiotic Resistance where bacteria may conquer upon
crisis,” An estimated 140,000 health us.so, to execute this condition we
care–associated Enterobacteriaceae need to stop misuse of antibiotics.
infections occur in the U.S. each Coordinated efforts to implement
year; 9,300 of these are caused by new policies, renew research efforts
CRE. Each year, approximately for development of new antibiotic
600 deaths result from infections agents by pharmaceutical companies
caused by the two most common to address the challenge, arising
types of CRE, carbapenem-resistant issue of antibiotic resistant on R
Klebsiella species and carbapenem- and D units, Developing skills,
resistant E. coli (Ventola, 2015,april) knowledge and well manpower
” . Also according to Research on new antibiotics manufacturing
Paper “Antibiotic Resistant Bacteria, and pursuing steps to manage the
Tuberculosis, once fatal, has made global health crisis by any certified,
a major comeback across the globe, well-trained physicians, pharmacist
and has mutated into a resistant or pharmaceutical companies or
strain known as MDR TB (Multi by us are greatly needed. Unless a
drug Resistant TB), resulting steps towards for defending against
in 150,000 annual deaths. The resistant bacteria strived, then of
development of MDR TB has been course our life and health will surely
linked to the HIV/AIDS epidemic. swing on bacteria’s hand, their
(Research Papers on Antibiotic intention, our health conditions may
Resistant Bacteria). be in risk. So we need to rise along
with a slogan, “STOP MISUSE OF
Antibiotics resistance by pathogens ANTIBIOTICS, UNLESS THEN
may developed due to overuses GLOBAL CRISIS” for to aware entire
of antibiotics, inappropriate world. If not we stopped and still
prescription and dispensing of continue of misusing antibiotics on
antibiotics caused by any well larger dosages for treatment of minor
trained/certified physicians to minor bacterial infections, then , I still
bacterial infections. Also, globally wonder,” Do we are eating antibiotics
the manufactured new antibiotics for bacteria or bacteria are eating
are very few in number and there’s antibiotics for us?”
availability of New Antibiotics
having new mechanism of action to
act upon pathogens are declining
at the same time increasing in no
of resistant and mutant bacteria
also making us in very difficult