Page 20 - P4304.1-V90_PS-Magazine-October 2023 - PRINT

Acepiro Prescribe Acepiro
Acepiro
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600 mg Effervescent Tablets by brand
600 mg Effervescent Tablets

Acetylcysteine
Acetylcysteine

Take a look at all the remaining study days coming up in 2023.
Acepiro is indicated in adults as a mucolytic agent
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Dates and locations for 2023 for the treatment of respiratory tract diseases in SIMPLE
which a reduction in bronchial secretion viscosity is
required to facilitate expectoration.
1
October November EFFECTIVE
Prescribing Acepiro by brand is the least
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expensive way of prescribing a mucolytic even
3 Blandford Forum 8 Plymouth 16 Norwich* compared to prescribing by generic name .
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th
rd
2,3
12:00 - 16:00 Clinical & Commercial 12:00 - 16:00 Understanding the Drug 09:00 - 12:30 Exploring the value of ECONOMICAL
Considerations for DDs Tariff & Endorsing social media in DDs Prescribing Acepiro (Acetylcysteine
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Caroline Pond Caroline Pond Marie Ennis O’Connor
600 mg effervescent tablets) by brand would save
4 Chepstow 9 Redruth* 12:30 - 16:30 Clinical & Commercial £18.26m to the NHS when compared to generic
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Considerations for DDs
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12:00 - 16:00 Clinical & Commercial 12:00 - 16:00 Dealing with VAT in Caroline Pond Carbocisteine, Mucodyne , generic Acetylcysteine
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Considerations for DDs practice and Nacsys . (PACT data to February 2023).
Caroline Pond Jim Mandeville
22 Tunbridge Wells* Manufacturer Discount Scheme available to
nd
5 Chester 12:30 - 16:30 Clinical & Commercial 09:00 - 12:30 Dealing with VAT in dispensing practices offering a discount of 30%
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Considerations for DDs
practice
12:00 - 16:00 Time Management Caroline Pond Jim Mandeville
Skills
PIP
NHS
Martyn Potter 14 Lincoln 12:30 - 16:30 Clinical & Commercial Product Code Price MDS Net Rebate
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Considerations for DDs
10 Harrogate 12:00 - 16:00 Clinical & Commercial Caroline Pond Acepiro 600mg 4197638 £3.65 30% £2.56 £1.09
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Considerations for DDs
12:00 - 16:00 Time Management Skills Caroline Pond *Delegates can attend the effervescent tablets x20
Martyn Potter event as a full day event or
just attend one of the two
15 Huntingdon session if they wish. Lunch will *Compared to generic and branded carbocisteine and generic and branded acetylcysteine (Nacsys ).
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11 Preston 12:00 - 16:00 Understanding the Drug be provided for all. ®
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Tariff & Endorsing
patients treated with acetylcysteine – hypersensitivity reactions, headache, tinnitus,
12:00 - 16:00 Clinical & Commercial Caroline Pond Acepiro 600 mg effervescent tablets – Abbreviated have been reported by at least one in a thousand and less than one in a hundred
Prescribing Information
Considerations for DDs tachycardia, stomatitis, abdominal pain, nausea, vomiting, diarrhoea, pruritus,
Caroline Pond Penrith Please refer to the Summary of Product Characteristics (SmPC) before prescribing urticaria, exanthema, rash, angioedema, pyrexia and lowered blood pressure. The
incidence of facial oedema has not been established. Overdose There have been
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Acepiro 600mg effervescent tablets.
Each tablet contains 600 mg acetylcysteine. Uses Acepiro is indicated in adults as a no reports of toxic overdose with oral acetylcysteine. In the case of an overdose of
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Acepiro , management should be supportive. Effects on the ability to drive and/or
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12 Penrith Scarborough mucolytic agent for the treatment of respiratory tract diseases in which a reduction operate machines Acepiro has no effect on the ability to drive or operate machines.
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in bronchial secretion viscosity is required to facilitate expectoration. Dosage and
Administration One tablet daily after food. Each tablet should be dissolved in half a Legal category: POM
12:00 - 16:00 Understanding the Drug Harrogate glass of water. Duration of therapy should be determined by the treating physician. Pack size: 20 or 30 effervescent tablets in strips of laminated aluminium paper foil.
Tariff & Endorsing Special Warnings and Precautions Hypersensitivity to the active substance or Shelf life: 3 years.
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to any of the excipients. Acepiro should not be used by adolescents or children.
Caroline Pond Preston Use with caution in patients with a history of asthma or bronchospasm. Should NHS price: 20 effervescent tablets = £3.65
bronchospasm occur Acepiro should be discontinued immediately. Very rarely, 30 effervescent tablets = £4.40
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serious skin reactions such as Stevens-Johnson syndrome and Lyell syndrome have Marketing Authorisation Holder: Stirling Anglian Pharmaceuticals Ltd, Hillington
31 Scarborough Chester been reported. Patients should be advised to seek immediate medical advice in the Park Innovation Centre, 1 Ainslie Road, Hillington Park, Glasgow G52 4RU
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presence of new skin or mucosal lesions. Administer with caution in patients with
a reduced cough reflex for example elderly or frail patients. Postural drainage and Marketing Authorisation Number: PL 42582/0015
12:00 - 16:00 Clinical & Commercial Lincoln broncho-aspiration should be performed in patients unable to cough up bronchial Further information is available at medinfo@stirlinganglianpharmaceuticals.com
Considerations for DDs secretions effectively. Incompletely dissolved tablets present a risk of choking and or via the office number 0141 585 6352
Caroline Pond aspiration, particularly to elderly patients. Use with caution in patients with a history Date of preparation: 23 December 2022
of peptic ulcer disease or histamine intolerance. Hepatic and renal impairment
Norwich can reduce clearance and increase systemic acetylcysteine plasma levels which Unique Code: API-004-22-001 2.0
may result in an increase in adverse drug reactions due to drug accumulation.
Contraindications Hereditary problems of galactose intolerance, total lactase 0040030021 v 1.0 | Date of preparation: May 2023
Chepstow Huntingdon deficiency or glucose-galactose malabsorption. Interactions with other medicinal Adverse events should be reported. Reporting forms and information can
products In vitro tests indicate that (tetracycline, aminoglycosides and penicillin
are inactivated when mixed directly with acetylcysteine. Where concomitant use be found at http://yellowcard.mhra.gov.uk or downloaded from Google Play
or the Apple App store. Adverse events should also be reported to JensonR+
of Acepiro and oral antibiotics is required, separate administration by an interval on 01271 314 320 or Stirling Anglian Pharmaceuticals on 0141 585 6352.
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of at least two hours. Acetylcysteine may potentiate the vasodilatory effect of
Scan QR nitroglycerine. Do not administer concurrently with ACE inhibitors or antitussives.
Acetylcysteine may reduce the bioavailability of certain heavy metal salts and should
be taken separately at different times of the day. Pregnancy fertility and Lactation
code to Administration of acetylcysteine during pregnancy and lactation should take
place only after a strict risk benefit assessment. Side Effects The following events
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References:
20 PS Magazine | PSUK live Buy direct online at PSUK.co.uk 1. Acepiro Summary of Product Characteristics. Available at https://www.medicines.org.uk/emc/product/13849/. Date accessed May 2023
2. British National Formulary available at https://bnf.nice.org.uk/drugs/acetylcysteine. Date accessed May 2023
3. NHS England and Wales Drug Tariff March 2023 available at https://www.drugtariff.nhsbsa.nhs.uk/#/00834576-DD_1/DD00834564/Home. Date accessed May 2023
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