Page 33 - D:\Video IPSyoFS22\

Synthesis and characterization of magnesium oxide nanoparticles using Syzygium cumini and
evaluation of In vitro anti-oxidant and anti-microbial activity of MgONPs

1 Sai Manogna Kotakadi, John Sushma Nannepaga *
1

1 Department of Biotechnology, Sri Padmavati Mahila Visvavidyalayam, Tirupati, Andhra Pradesh.

* Corresponding author: johnsushma@gmail.com

Abstract:

Syzygium cumini is one of the widely used medicinal plants in the treatment of various diseases
particularly diabetes. The present study has been focused on the synthesis of magnesium oxide
nanoparticles (MgONPs)using seed extract of S. cumini and to observe their anti-oxidant and
antimicrobial activity. The synthesized nanoparticles were characterized by performing UV-Vis
spectrophotometer, FTIR, and SEM. UV visible spectroscopic analysis revealed the Surface Plasmon
Resonance (SPR), the final reaction product confirming the reduction of magnesium ions to MgONPs.

FTIR analysis of synthesized MgONPs showed the presence of carboxylic acids, amides, aldehydes,
alcohols, ketones and phosphines at different band positions at 3263.46 cm-1, 2839.03 cm-1, 1646.17
cm-1 and 1015.16 cm-1. SEM analysis showed crystalline nature at 500 nm. Subsequently tested
antimicrobial activity of MgONPs of Syzygium cumini. MgONPs showed more antibacterial activity on
E. Coli, Streptococcus pneumonia, Staphylococcus aureus and Salmonella typhimurium. Hence, these
MgONPs can be used as an antimicrobial agent in treating many medical complications.

Keywords: Syzygium cumini, MgONPs, SEM, Anti-oxidant activity, Anti-microbial activity.