Page 75 - e-book CPG - Bipolar Disorder

CLINICAL PRACTICE GUIDELINES MANAGEMENT OF BIPOLAR DISORDER (2ND ED.)

Appendix 9 haloperidol is used alone. of cases but occurred, Appendix 9 in metabolites its receiving women that Appendix 9 to reason a not is it of have especially while nursing a cases but occurred, preferred in a dose-related manner. become data more but

LACTATION LACTATION However, use with other APs occasionally might negatively affect the An alternate drug may be preferred, especially while nursing a newborn or preterm infant due to limited information available. Aripiprazole can lower serum prolactin in a dose-related manner. Monitor infan
adverse developmental effects when NOT RECOMMENDED DURING LACTATION. lactation of especially if other APs are used concurrently. infants whose mothers were taking aripiprazole. of amounts **Relative Infant Dose (RID): 0.7 - 8.3%. labelling any AEs in breastfed infants. asenapine should not breas

  infant. Monitoring:   o Cases   breastfeeding. However,   Manufacturer’s   asenapine If      Aripiprazole can   Cases      alternate An Cases  available.    Manufacturer’s   **RID: 0.3 - 4%. 
the in THIRD the the in in the and limited. in
aripiprazole, RISK aripiprazole, aripiprazole, aripiprazole, ANIMAL trimester if possible, pregnancy 60
SUMMARY OF MEDICATIONS FOR BIPOLAR DISORDER WITH PREGNANCY AND LACTATION  SUMMARY OF MEDICATIONS FOR BIPOLAR DISORDER WITH PREGNANCY AND LACTATION  SUMMARY OF MEDICATIONS FOR BIPOLAR DISORDER WITH PREGNANCY AND LACTATION asenapine IN  SUMMARY OF MEDICATIONS FOR BIPOLAR DISORDER WITH PREGNAN

with of use the POTENTIAL with with of use the PREGNANCY SUGGEST MODERATE of use the weight maternal with DATA in of use the DATA for use in pregnancy; however, if DATA ANIMAL DATA ANIMAL DATA ANIMAL
Avoid first trimester exposure if possible. HUMAN DATA SUGGEST LOW RISK. Aripiprazole crosses placenta. requires to reduce risk of AEs. condition defects, miscarriage, maternal or foetal outcomes. adequate no HUMAN DATA SUGGEST LOW RISK. Aripiprazole crosses placenta. DATA HUMAN effects were
PREGNANCY PREGNANCY Preferred drug if first generation APs is needed in pregnant patients. However, minimum effective dose should be used Due to limited data, avoid use in pregnancy. However, if the treatment lowest effective dose, avoiding the first trimester if possible, Insufficient data

     mother’s should be used.  RISK. are There  LIMITED   TRIMESTER.    mother’s  lowest  should be used.  mother’s RISK.  RISK.  should be used.    RISK. RISK. maternal use. are There    pregn

MEDICATION MEDICATION Aripiprazole* Lumateperone* Asenapine* MEDICATION Aripiprazole* Lurasidone* MEDICATION Aripiprazole* Cariprazine* Olanzapine* Asenapine* Clozapine* Asenapine* MEDICATION Aripiprazole* Haloperidol* Cariprazine* Paliperidone* Cariprazine* Clozapine*

ANTIPSYCHOTICS ANTIPSYCHOTICS ANTIPSYCHOTICS ANTIPSYCHOTICS

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