Page 79 - e-book CPG - Bipolar Disorder

CLINICAL PRACTICE GUIDELINES MANAGEMENT OF BIPOLAR DISORDER (2ND ED.)

unusual jaundice

LACTATION LACTATION LACTATION Valproate levels in breastmilk are low and infant’s serum levels Valproate levels in breastmilk are low and infant’s serum levels Valproate levels in breastmilk are low and infant’s serum levels range from undetectable to low. Breastfeeding durin
POSSIBLE TO USE IN LACTATION. POSSIBLE TO USE IN LACTATION. POSSIBLE TO USE IN LACTATION. infants Breastfed bruising or maternal therapy. or bleeding.

      development. development. development.    Monitoring:  Monitoring:  o Monitoring:  o o o
for for for to to in-utero and to and and bearing bearing bearing to prior to to
consultation, consultation, consultation, in-utero exposed in-utero exposed exposed malformations malformations malformations child of women child of child of discontinued prior discontinued prior discontinued **In general, RID <10% is considered compatible with breastfee

PREGNANCY PREGNANCY PREGNANCY CONTRAINDICATED and an alternative treatment should be CONTRAINDICATED and an alternative treatment should be CONTRAINDICATED and an alternative treatment should be specialist specialist appropriate appropriate specialist appropriate children potential children a

with women planning pregnancy. potential potential a high have mental disorders. high a not be be not be not valproate valproate valproate Clinical Drug Information, Inc. Wolters Kluwer. UpToDate® [Mobile application software]. Clinical Drug Information, Inc. Wolters Kluwer. Up
with on, with women planning pregnancy. women planning pregnancy. and teratogenic have neurodevelopmental disorders. neurodevelopmental disorders. must must must with with with In case of pregnancy consider alternative options. consider alternative options. consider alternative o
on, on, teratogenic teratogenic a have neurodevelop Pregnancy test use in pregnancy. Contraception Pregnancy Planning Pregnancy Planning Pregnancy Planning In case of pregnancy In case of pregnancy agents, breastfeeding is considered acceptable if RID is <5%. 4,5 agents, breastfe
decided High valproate valproate valproate Pregnancy test Pregnancy test Treatment Treatment Treatment use in pregnancy. use in pregnancy. Contraception Contraception Treatment Treatment Treatment

 decided decided  High High    
           

MEDICATION MEDICATION
MEDICATION Valproate Valproate Valproate Source: Source: 1. Source: 2. 3. 4. 5.
1. 1. 2. 2. 3. 3. 4. 4. 5. 5.
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