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Clinical pharmacy PharmD program                     Third level                          Phytochemistry-1 (PG-504)





























                                                Sesquiterpenes

              A- Acyclic sesquiterpenes:

              Sesquicitronellene & Farnesene

              Occurrence: Oil of citronella.

              Preparation: by fractional distillation.

              Uses:

                 1.  In scenting soap and cosmetics.
                 2.  On digestion with formic acid, it gives the monocyclic sesquiterpene “Bisabolene”,
                     which is a precursor for the preparation of bisabolol (anti-inflammatory).

                                      14

                                    6         8
                                5         7        9

                                        12         10
                                4
                                    3        11       15


                                     2
                                13        1
                              Sesquicitronellene                    Farnesene







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