Page 94 - Interactive Theoritical Notes of Bioharmaceutics and pharamcokinetics.docx compressed
P. 94

PharmD clinical pharmacy program            Level 3, Semester 2          Biopharmaceutics & Pharmacokinetics (PT608(



                                   An ion pair is formed in which the overall charge of the pair is neutral.

                               This neutral drug complex diffuses more easily across the membrane.










                          For example, the formation of ion pairs to facilitate drug absorption



                          a basic drug that forms an ion pair with oleic acid


                          which forms ion pair with hexylsalicylate.




                  Factors affecting drug absorption from GIT






































                                                                 93
   89   90   91   92   93   94   95   96   97   98   99