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Unlike synthetic nanoparticles or purified protein shots,
               plant-based tolerizing vaccines are biologically familiar,
               mimicking the way the immune system evolved to interpret
               harmless proteins. This helps:


                   •  Prevent immune activation
                   •  Promote regulatory phenotypes
                   •  Reduce anti-drug antibodies (ADA)
                   •  Enable long-term persistence of the therapeutic
                       effect

               This isn’t immunosuppression.
               It’s immune retraining—antigen-specific, durable, and
               rooted in the body’s own logic.



               A Platform for Preemption, Not Just Treatment


               Tolerizing vaccines are not just a new kind of biologic.
               They represent a new kind of immune medicine—with
               implications far beyond autoimmune disease.


               Imagine:

                   •  Giving at-risk children oral insulin peptides to
                       prevent Type 1 diabetes
                   •  Delivering gliadin antigens to young patients
                       genetically predisposed to celiac disease
                   •  Desensitizing allergy sufferers with edible peanut or
                       dust mite proteins, without risking anaphylaxis
                   •  Calming inflammation at the source in Crohn’s or
                       ulcerative colitis—without suppressing the entire
                       immune system





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