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Chapter 19: Congestive Heart Failure  279


              diocentesis  is  common  in  cats  with  congestive  heart   aortic cusps is obtained, and the first diastolic frame in
              failure. Moderate or severe pericardial effusion can cause   which closure of the aortic valve is evident is selected.
              cardiac tamponade and right heart failure. Careful dis-  The aortic diameter (Ao) is measured by a line parallel
              tinction of pleural and pericardial effusion is necessary.   to the commissures of the right coronary and noncoro-
              The pericardium should be identified at its attachment   nary cusps, using the inner edge method (the internal
              to the heart base and is helpful to distinguish pleural   diameter of the structure is measured not including the
              from pericardial effusion. Cardiac tamponade is subjec-  wall thickness) (see Chapter 7). The left atrial diameter
              tively  assessed  by  visualization  of  diastolic  collapse  of   (LA) is measured by a line parallel to the commissure of
              the right atrium and/or right ventricle. The left ventricle   the  left  coronary  and  noncoronary  cusp,  with  care  to
              often appears underloaded when there is cardiac tam-  avoid the pulmonary vein insertion into the left atrium.
              ponade.  This  appears  as  a  small  ventricular  internal   An  LA : Ao >1.5  indicates  left  atrial  dilation. Although
              diameter  during  diastolic  and  systole,  and  possibly   the degree of left atrial dilation is subjective, suggested
              mildly thickened left ventricular wall and septum (pseu-  criteria for mild, moderate, and severe left atrial dilation
              dohypertrophy). Accurate left ventricular measurements   are LA : Ao 1.51–1.79, 1.79–1.99, and ≥2.0, respectively.
              are only possible once the cardiac tamponade has been   Left atrial dilation is usually moderate to severe in cats
              relieved. If there is life-threatening cardiac tamponade,   with heart failure. Sometimes the left atrial size decreases
              immediate pericardiocentesis should be done prior to a   to be only mildly dilated after acute aggressive diuretic
              comprehensive echocardiogram. However, if the patient   therapy. If left atrial size is normal, it is highly unlikely
              is reasonably stable, a detailed echocardiogram should   that congestive heart failure is the cause of pulmonary
              be  done  to  evaluate  for  cardiac  or  pericardial  masses,   infiltrates, and the cat should be evaluated for primary
              which are better visualized in the presence of pericardial   respiratory diseases. One exception is the cat that has   Congestive Heart Failure
              effusion.                                          undergone an acute exacerbating event, such as intrave-
                 Identification  of  significant  left  and/or  right  atrial   nous fluids, acute tachycardia, anesthesia in the preced-
              dilation is essential to establish the diagnosis of conges-  ing  48  hours,  or  Depo-Medrol®  or  other  long-acting
              tive  heart  failure  versus  primary  respiratory  disease,   glucocorticoid injection in the preceding 7 days, where
              which has immediate treatment implications. Left atrial   the left atrial size may not be markedly dilated in the
              dilation suggests that the left atrial pressure is elevated,   face of congestive heart failure. Extremely rare causes of
              which  occurs  secondary to  systolic myocardial failure,   cardiogenic pleural effusion in the face of normal atrial
              diastolic  dysfunction,  valvular  insufficiency,  or  left  to   size are constrictive pericarditis or a mass or an intralu-
              right shunting congenital heart diseases. Presence of sig-  minal cranial vena caval thrombus or mass. Pulmonary
              nificant left atrial enlargement indicates severe cardiac   edema and/or pleural effusion may be seen in cats with
              disease  and  implies  a  poorer  long-term  prognosis,   significant  left  atrial  dilation  and  left  heart  failure,
              although  there  is  tremendous  individual  variation   whereas right atrial dilation and right heart failure lead
              regarding disease progression, response to therapy, and   to pleural effusion and/or ascites and pericardial effu-
              survival. Left atrial enlargement is an independent pre-  sion. Right atrial size is subjectively evaluated from the
              dictor for serious adverse cardiac events in people with   right parasternal long-axis 4-chamber view and the right
              HCM and was associated with more severe diastolic dys-  parasternal cross-sectional view at the heart base. The
              function and higher filling pressures (Yang et al. 2005).   right atrium is normally smaller than the left atrium and
              Likewise, increased left atrial size is negatively correlated   is  dilated  when  it  is  subjectively  larger  than  the  left
              with survival time in cats with HCM (Rush et al. 2002).   atrium. In cats with atrial dilation, it is essential to care-
              The left atrial size is measured from a right parasternal   fully evaluate for spontaneous echocardiographic con-
              cross-sectional view at the level of the aortic valve (see   trast  or  a  thrombus  within  the  dilated  atrium  (see
              Chapter  7).  The  left  atrium  and  aortic  diameters  are   Chapter 20).
              measured either from a two-dimensional image or by   Myocardial structure and function are assessed from
              using M-mode with the cursor placed through the body   the  right  parasternal  cross-sectional  view  at  the  level
              of the left atrium and the aorta. The ratio of left atrial   of the left ventricular papillary muscles. The fundamen-
              diameter to aortic diameter (LA : Ao) is used to eliminate   tal  objectives  for  the  triage  echocardiogram  are  to
              the influence of body size on left atrial size, and provides   (briefly) assess myocardial structure and function and
              a  dimensionless  index  of  atrial  size.  Two-dimensional   identify whether there is markedly reduced myocardial
              echocardiography is recommended for measurement of   systolic  function  (e.g.,  dilated  cardiomyopathy),  overt
              left atrial size, since it is not limited by the location and   concentric hypertrophy of the left ventricular wall and
              alignment of the cursor when using M-mode. The right   septum,  or  the  ventricle  appears  relatively  normal  in
              parasternal  short-axis  basilar  view  at  the  level  of  the   structure and function. Cats with an overtly thickened
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