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Chapter 10: Congenital Heart Malformations  95


              Treatment                                          Differential Diagnosis
              Because  the  majority  of  cats  with  atrial  septal  defects   The clinical, radiographic and echocardiographic find-
              remain asymptomatic, treatment is not generally needed.   ings  of  supravalvular  mitral  valve  stenosis  are  very
              Cats with large defects and volume overload may benefit   similar to those of cor triatriatum sinister. The position
              from angiotensin-converting enzyme inhibitors such as   of the obstructing membrane relative to the left auricle
              enalapril or benazepril. Large defects may result in the   as noted on a two- dimensional echo, 4-chamber, right
              development of heart failure and should be treated as   parasternal  view  may  help  differentiate  the  two.  Cor
              described (see Chapter 19).                        triatriatum  should  be  suspected  if  the  left  auricle  is
                                                                 located distal to the dividing membrane and supraval-
              Prognosis                                          vular stenosis should be suspected if the left auricle is   Congenital Heart Disease
                                                                 located proximal to the dividing membrane (Fine et al.
              The prognosis is typically dependent on the size of the
              defect. Cats with small atrial septal defects may remain   2002).
              asymptomatic for life.                             Diagnostic Testing
                                                                 Electrocardiography
              COMMON AV CANAL (ENDOCARDIAL                       A right axis shift was observed in one case (Koie et al.
              CUSHION DEFECT)                                    2000).
              This  developmental  malformation  is  characterized  by   Radiography
              absence of the lower/basal atrial septum, higher/dorsal   Radiographs  may  indicate  signs  of  left  heart  failure
              ventricular septum, and malformation of the atrioven-  including  pulmonary  venous  congestion  and  pulmo-
              tricular valves (mitral and tricuspid).            nary edema.


              Pathophysiology                                    Echocardiography
              The  resultant  abnormality  leads  to  communication   Echocardiography should identify a double chamber left
              between  all  the  chambers  and  results  in  heart  failure   atrium with a dilated proximal chamber (Figure 10.5).
              usually by 1 year of age.                          The atrium should appear to be divided by a membrane
                                                                 with a small communication between the two chambers.
                                                                 The  left  auricle  should  be  associated  with  the  distal
              COR TRIATRIATUM SINISTER                           chamber  as  noted  on  a  two-dimensional,  4-chamber,
                                                                 right parasternal view echocardiogram.
              Cor triatriatum sinister is an uncommon defect in the
              cat (Gordon et al. 1982; Wander et al. 1998; Koie et al.   Treatment
              2000; Heaney and Bulmer 2004). It is characterized by
              the  presence  of  a  band  of  tissue  that  divides  the  left   Kittens with cor triatriatum often present with clinical
              atrium resulting in 2 left atrial chambers, which com-  signs of congestive heart failure that should be addressed
              municate  through  a  small  opening.  One  chamber   as described (see Chapter 19). Surgical correction of cor
              receives  the  pulmonary  venous  flow  and  the  second
              chamber communicates with the mitral valve.


              Pathophysiology
              Because of the small communication between the two,
              obstruction of blood flow occurs between the two cham-
              bers.  The  pressure  in  the  proximal  chamber  becomes
              elevated, the chamber dilates, and increased pressure is
              reflected to the pulmonary veins. Left-sided heart failure
              usually results.


                                                                 Figure  10.5.  Right-sided	 long-axis	 4-chamber	 echocardio-
              Physical Examination
                                                                 graphic	 view	 from	 a	 cat	 with	 cor	 triatriatum	 sinister.	Note	 the
              A heart murmur is typically detected on the left side.   double	chamber	left	atrium	(LA	in	2	locations,	separated	by	the
              Both systolic and diastolic murmurs have been reported   partitioning	membrane	[arrow]),	with	a	dilated	proximal	chamber.
              (Wander 1998; Heaney and Bulmer 2004).             LV	=	left	ventricle;	RA	=	right	atrium;	RV	=	right	ventricle.
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