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Chapter 10: Congenital Heart Malformations  97


                                                                 History and Chief Complaint
                                                                 In  one  study,  the  most  common  clinical  presentation
                                                                 included abnormal respiration, exercise intolerance, and
                                       AO
                                                                 poor growth (Hitchcock et al. 2000).

                                                                 Physical Examination
                                   PA
                                                                 Although the heart murmur of a patent ductus arterio-
                                                                 sus  is  typically  continuous,  in  about  1/3  of  the  feline
                                                                 cases in one study, only the systolic component of the
                                                                 murmur  was  heard  (Hitchcock  et  al.  2000).  In  some   Congenital Heart Disease
                                                                 cases,  the  continuous  murmur  is  heard  best  ventrally.
                                                                 Hyperkinetic  pulses  were  identified  in  about  1/3  of
                                                                 feline cases.


                                                                 Diagnostic Testing
                                                                 Electrocardiography
              Figure 10.6.  Heart	from	a	cat	with	a	patent	ductus	arteriosus	  A  normal  sinus  rhythm  and  normal  axis  may  be
              (PDA).	The	arrow	indicates	the	patent	ductus	connecting	the	de-  observed, but left ventricular chamber enlargement pat-
              scending	 aorta	 (Ao)	 and	 the	 pulmonary	 artery	 (PA).	 Moderate	  terns may be observed.
              right	ventricular	enlargement	is	also	seen.

                                                                 Radiography
                                                                 The most commonly reported radiographic abnormal-
              pressure  in  the  aorta  is  naturally  always  higher   ity  is  cardiomegaly.  Left-sided  enlargement  would  be
              (120/80 mm Mg) than the pulmonary artery (25/12 mm   expected,  with  pulmonary  overcirculation  also  com-
              HG). Shunting of blood occurs both though systole and   monly expected. The cardiac apex may be displaced to
              diastole and is, therefore, a continuous shunt. The shunt-  the right.
              ing of blood from the aorta to pulmonary artery results
              in  left-sided  volume  overload  as  the  blood  circulates   Echocardiography
              through  pulmonary  artery  and  veins,  back  to  the  left   Echocardiography is needed to confirm the diagnosis.
              atrium and ventricle, and through the aorta and pulmo-  Doppler echocardiography should in the region of the
              nary artery again. Left heart failure may develop.  pulmonic  valve  and  ductus  should  show  continuous
                 Some  cats  develop  elevated  pulmonary  artery  pres-  flow  shunting  into  the  pulmonary  artery  from  the
              sure,  likely  due  to  the  impact  of  the  increased  blood   ductus  (Figure  10.7).  It  can  be  quite  challenging  to
              volume on pulmonary vasculature (Eisenmenger’s phys-  image the actual ductus in a cat, particularly a kitten.
              iology), as described for ventricular septal defects. The   Cats  that  develop  pulmonary  hypertension  may  show
              elevated pulmonary pressures may become high enough   signs of right ventricular hypertrophy.
              to result in a reversal of the direction of the shunt, now
              shunting  from  pulmonary  artery  to  the  descending
              aorta. These patients may develop polycythemia and dif-  Treatment
              ferential cyanosis as the deoxygenated blood from the   Because  patients  with  patent  ductus  arteriosus  may
              pulmonary  artery  is  shunted  to  the  descending  aorta.   develop left heart failure and pulmonary hypertension,
              Irreversible changes in the pulmonary vasculature may   repair is almost always advised. Surgical ligation of the
              develop.                                           defect is most common, but transvenous embolization
                                                                 with a detachable coil has also been reported in 2 cats
              Signalment
                                                                 (Schneider  and  Hildebrandt  2003;  Summerfield  and
              Specific breed predispositions or genders with increased   Holt 2005). Uncommonly an older cat may present with
              predisposition have not been noted.                a patent ductus arteriosus that was not diagnosed at a
                 The patent ductus arteriosus is an uncommon defect   young age. In some cases, if the patent ductus arteriosus
              in  the  cat;  therefore,  specific  signalment  prevalences   is small with little volume overload, surgical correction
              have not been defined.                             may not be needed.
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