Page 1265 - Veterinary Toxicology, Basic and Clinical Principles, 3rd Edition

1196 Index

VetBooks.ir Ramaria flavo-brunnescens, 963 964 postapproval surveillance activities, 96 100 Reptilia, 792 798
tests, 147 148, 148t
center for veterinary medicine, 91 96
organization, 90
Ranitidine, 370, 378
Raptors, 46 47
crotalids, 792 795
Ras, 349
Relay toxicosis, 711
lizards, 796 798
“Ratak”, 586 Relative biologic effectiveness (RBE), 328 elapids, 796
Rational Questionnaire (RQ), 97 Reliable traceability systems, 112 snakes, 792 796
Rationale for livestock recommendations, RELs. See Recommended Exposure Levels Residual volume, 216 217
1106 1112 (RELs) Residue “loading", 122 123
Rattle snake envenomation, 216 Renal calculi, 1070 Residue chemistry studies, 95
Rattus norvegicus. See Norway rats (Rattus Renal cortical fibrosis, 1069 Residues, 136 137
norvegicus) Renal disease, 458 Resorcylic acid lactone, 737 738
Rayless goldenrod (Haplopappus Renal effects, 370 Respiratory depression, 391
heterophyllus), 867 868 Renal excretion, 244 Respiratory syndrome, 844
distribution, 867 Renal histology, 1070, 1070f Respiratory system, 215, 711
prevention and treatment, 867 868 Renal lesions, 267 268, 991 Respiratory toxicity. See also Lung injury
toxicology, 867 Renal papillary damage, 368 gas exchange region, 216 218
RBCs. See Red blood cells (RBCs) Renal papillary injury, 266 principles in pathogenesis of lung damage,
RBE. See Relative biologic effectiveness Renal pathology, 1069 218 221
(RBE) of petroleum, 666 respiratory system, 215
REACH. See Registration, Evaluation, Renal pyramids, 259 upper airways, 215 216
Authorization and Restriction of Renal selenium elimination, 472 Respiratory toxicosis, 215
Chemicals (REACH) Renal system, mercury toxicity, 459 Restrotation grazing systems, 843
Reactive nitrogen species (RNS), 434 Renal toxic mushrooms, 963 Resveratrol, 805 806, 806f
Reactive oxygen production, trichothecene- Renal toxicity, 259, 459 Retrorsine, 904
induced, 1045 functional anatomy, 259 261 Retroviruses, 350
Reactive oxygen species (ROS), 227, nephrotoxic agents, 266 271 Reverse transcriptase polymerase chain
245 246, 351, 433 toxic effects on kidney, 261 262 reaction (RT-PCR), 156
Reactive skin decontamination lotion (RSDL), Renal tubular injury, 269 Reversed-phase chromatography (RPC), 164
84 Renal vasoconstriction, 261 Reynolds numbers (Re), 220
Receptor agonism, 277 Renshaw cells, 203 204 RfC. See Reference concentration (RfC)
Receptor antagonism, 277 Reoxidation, 556 557 RfD. See Reference dose (RfD)
Recirculation systems, 734 735 Repartitioning agents, 107 Rhizoctonia leguminicola (R. leguminicola),
Recluse spiders (Loxesceles spp.), 782 Repeated implanting, 111 1029
Recommended Exposure Levels (RELs), 28 Reporting limits, 1135 Rhodanese, 938 939
Red blood cells (RBCs), 433, 725, 1156 Reproduction, 273 274 Rhododendron (Rhododendrum hirsutum), 54,
Red clover (Trifolium pratense), 48, 817 819, disruption, 975 63 64, 229 230
1029 effects Rhodonderon spp., 229 230
Red kites (Milvus milvus), 593 of gossypol on female, 977t Ribotoxic stress response, 1045
Red squill, 618 619, 618f of gossypol on male, 976t Ricin, 903
mechanism of action, 618 mechanisms and effects of reproductive Ricinoleic acid, 380
toxicity, 618 619 toxicants, 296 312 Ricinus communis. See Castor bean (Ricinus
toxicokinetics, 618 normal animal reproduction, 280 296 communis)
treatment, 619 toxicity testing, 94 Rifampicin, 363, 364t
Red-tailed hawks (Buteo jamaicensis), 593, 719 Reproductive abnormalities, 473 474 Rifampin, 584
Redoul. See Coriaria myrtifolia (Coriariaceae Reproductive effects, 990 Risk, 9 10
family) Reproductive stem, 899 analysis paradigm, 9 10
Redox reactions. See Reduction and oxidation Reproductive system, 823 characterization, 118 119
reactions (Redox reactions) Reproductive toxicants, 275 Risk assessment (RA), 111, 829 830, 1060
Redox recycling process, 556 557 affecting female reproductive function, implications for, 810 811
Reduction and oxidation reactions (Redox 303 305 Risk Management Limit for Carcinogen (RML-
reactions), 250 affecting male reproductive function, CA), 28
“Reefers”. See Marijuana cigarettes 299 303 Risk paradigm, toxicology joined to, 9 15, 10f
Reference compartment, 135 effects RIT. See Rush Immunotherapy (RIT)
Reference concentration (RfC), 28 of EDCs, 296 298 Ritalin. See Methylphenidate
Reference dose (RfD), 28, 1106 on domestic animals, 298 RML-CA. See Risk Management Limit for
Reference point for action, 113 mechanisms and, 296 312 Carcinogen (RML-CA)
Regional gas dose ratios for human risk endocrine disruption RNA-activated protein kinase (PKR), 1045
assessment, 632 in humans, 297 298 RNS. See Reactive nitrogen species (RNS)
Registration, Evaluation, Authorization and in wildlife species, 297 “Roaring disease”, 844
Restriction of Chemicals (REACH), reproductive development and function in Robinia pseudoacacia. See Italy black locust
127 128, 691 692 males and females, 296f (Robinia pseudoacacia)
Regulatory considerations in veterinary susceptibility of pubertal process to, 281 Rochelle salt. See Sodium tartrate
toxicology teratogenesis and abortion, 305 312 Rock phosphate, 417, 429
FDA, 89 Reproductive toxicity, 274 275, 1046 Rodenticides, 40, 52