Page 444 - Withrow and MacEwen's Small Animal Clinical Oncology, 6th Edition
P. 444

422   PART IV    Specific Malignancies in the Small Animal Patient






  VetBooks.ir
















               A                                               B




















              C                                                D





















              E

                          • Fig. 22.17  Aggressive resection of injection-site sarcomas, with 5-cm lateral margins and one to two
                          uninvolved fascial layers for deeps margins, is required for the best opportunity for complete histologic
                          excision and local tumor control. (A) Planned lateral surgical margins are indicated with a sterile marker pen
                          5 cm in all directions around a body wall injection-site sarcoma. (B) An incision is then performed along the
                          marked margins. (C) Deep margins of two uninvolved fascial layers included chest (seven ribs) and body
                          wall. (D) After caudal lung lobectomy and diaphragmatic advancement, the body wall defect was recon-
                          structed with an omental pedicle graft and prosthetic mesh. (E) The wound defect was closed primarily.

         not appear to improve local control rates because local tumor recur-  the MST was significantly longer in cats treated with postoperative
         rence was reported in 42% of 59 cats with complete histologic exci-  rather than preoperative RT; however, the practice at this institu-
         sion and 32% of 28 cats with incomplete histologic excision. 234  tion was to treat larger tumors with preoperative RT and hence this
            The outcome after postoperative RT is similar to preoperative RT.   finding may be due to a selection bias.  In one study, local tumor
                                                                                            236
         In one study of 79 cats treated with surgery and curative-intent RT,   recurrence was reported in 41% of 76 cats at a median of 405 days
   439   440   441   442   443   444   445   446   447   448   449