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110                            Veterinary Laser Therapy in Small Animal Practice

                     Here are some examples of these calculations.      do well without treatment for a couple of months in the
                        •  If your peak power is 18 W and your average   warmer season. Others will do best when treated every
                           power is 12 W, that means you are working with   3–6 weeks for maintenance.
                           a 66.67% DC.                                   Most musculoskeletal conditions will need longer
                        •  If you know you are operating with a DC of 50%   sessions  or  appointments  than  wounds,  since  very
                           and the screen tells you the peak power is 6 W,   often there is more than one body area affected or sore
                           you know your average power is 3 W.          because of overload. Good orthopedic, neurological,
                        •  If you want to know how long your pulses are,   and biomechanical exams are essential to plan how
                           and you are working at 100 Hz with a duty cycle   many areas, how often, and how long will it take to
                           of 30%: 0.3 = 100 Hz × pulse duration, so pulses   apply the desired doses over the planned areas. This will
                           are 0.003 s or 3 ms. With that same DC, if you   influence the appointment length, and probably the fee
                           were pulsing at 2 Hz, those pulses would last 150   that is charged.
                           ms or 0.15 s.
                     •  Target different cell lines. Osteoblasts seem to    9.2 Laser therapy for fractures and
                        respond better to lower frequencies, for instance.              osteotomies

                        Therefore, a good strategy seems to combine both   Animal models have demonstrated that LT can increase
                     CW  and  different  pulsing  frequencies  (as  we  talked   bone mineralization. It stimulates osteoblastic activity
                     about at length in Chapter 8), which will also avoid a   by modulating bone morphogenic factors. The tissue
                     potential saturation of the biological response.   will have a higher number of active osteoblasts and
                                                                        they will be secreting more collagen matrix, so LT can
                                    9.1.4 How often?                    help fractures and osteotomies heal faster and produce
                                                                        a better organized and less exuberant callus. [160, 273–276]
                     As in wound management, acute conditions need lower   This will lead to stronger bone formation;  animals
                     doses but more often initially: daily for 2–3 days, then   treated with LT show higher maximum loads at failure
                     q48h for two to three more treatments, and then twice   in bone bending tests. [276, 277]  When we use LT in frac-
                     a week if needed until resolution. And chronic condi-  tures, the aim is to enhance biological processes that
                     tions need higher starting doses but they can be treated   contribute  to bone healing;  we can  influence growth
                     less often, although initially at least three treatments a   factor release, vascularization, osteogenic activity, and
                     week are recommended.                              inflammation.  Research  and  experience  have  proven
                        When dealing with a wound, a full resolution is   how important preserving the soft tissue and blood
                     the clinical expectation, but in many  chronic  mus-  supply is to fracture biology, and LT contributes to this.
                     culoskeletal problems the goal is to achieve a signifi-  If bone grafting is to be used in the fracture repair
                     cant improvement, then decrease the frequency of   procedure, LT can improve bone graft survival. Animal
                     visits, and find a maintenance regime that will ideally   models  show  that  LT  improves  incorporation  at  the
                     prevent relapses and improve the quality of life of the   graft–host interface, filling of osteocyte lacunae, and
                     patient, but will not cure or reverse the basic underly-  collagen deposition, while it decreases the inflam-
                     ing process. These phases are often named induction   matory infiltrate in the early postoperative period.
                     (we achieve the clinical effect with more frequent treat-  [275, 278, 279]
                     ments), transition (we maintain that but decrease the   These, together with the anti-inflammatory and
                     frequency), and maintenance. So after treating three   analgesic effects, are the reasons LT can improve frac-
                     times  a  week  (or  q48h),  usually  for  1–2  weeks,  and   ture repair and patient’s quality of life. Clinical studies
                     once an improvement is noted (not before!), LT can   (again, very few have been published) in humans show
                     be delivered twice a week (usually for 2–3 weeks), then   that patients achieve better analgesia and functional
                     once a week for 2–3 weeks. The maintenance regime   recovery in closed fractures of the wrist and hand.
                     after that will vary with the patient. For instance, an   [280]  Also, LT helps bone formation and healing after
                     old Labrador with degenerative joint disease (DJD) of   mid-palatal suture expansion in children [281]  and in
                     the hip may need to come again more often in the next   dogs, [161]  and may decrease orthodontic correction
                     cold/humid season, when his hips hurt more, but may   time. [282]










         REDONDO PRINT (4-COL BLEED).indd   110                                                                        08/08/2019   09:48
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