Page 588 - Veterinary Immunology, 10th Edition

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FIG. 19.6 The activities of NK cells. They kill stressed cells, cells
not expressing MHC class I, and antibody-coated targets. By
releasing IFN-γ, they also activate macrophages.

The second strategy uses NK receptors that recognize stress-

induced proteins on cells. When the NK cells detect these stress
proteins, an activating signal is generated and the NK cells kill the
stressed cells (Fig. 19.7). Cells infected by viruses and intracellular

bacteria, as well as some cancer cells, express these stress proteins.

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